Hello, I would like to ask you if it is possible to use CleanTag Small RNA library prep kit also for piRNA sequencing or if the adapters bind only to miRNAs? -Best, Petra

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Hello Petra,

CleanTag library preparation is a ligation based method that is designed to tag adapters onto small RNA species with a 3′ OH and 5′ P. piRNA is thought to have this type of structure and would therefore be compatible with the CleanTag kit.

Best Regards,

Joey