I am interested in an aptamer that would be able to detect a Salmonella typhimurium cell at one end and able to specifically hybridize to a ssDNA at the other end. Is it possible for you, and how difficult would that be for such an aptamer to achieve and maintain its 3D conformation in vitro? – Aristea

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Dear Aristea,

Thank you for your interest in TriLink BioTechnologies, Inc. Unfortunately, we do not offer aptamer design or selection services. We recommend Base Pair Bio who should be able to help you with your research needs.

We can synthesize the aptamer once the sequence is determined. Please let us know once you have a sequence identified and we will gladly provide a quotation.

Thanks,
Kaitlin

3 thoughts on “I am interested in an aptamer that would be able to detect a Salmonella typhimurium cell at one end and able to specifically hybridize to a ssDNA at the other end. Is it possible for you, and how difficult would that be for such an aptamer to achieve and maintain its 3D conformation in vitro? – Aristea”

  1. I’m buying a ssDNA library from Trilink and doing SELEX for one target. Assuming i will get one specific sequence that will bind with high specificity and affinity. My question is , Can I patent that sequence and start conducting a clinical trial then sell it without permission from Trillink? if so, is it possible to provide me with some reference .
    Thanks and really appreciate it

    -Alan

    • Dear Alan,
      TriLink does not take any claim on an aptamer sequence determined from one of our Nucleic Acid Libraries for Aptamer Selection. Please let us know if you need any additional information.

      Best regards,
      Joey

  2. Thank you Kaitlin, Aristea we can provide custom aptamers from Salmonella typhimurium targets and provide a hybridization sequence at the end as well, contact us directly at info@basepairbio.com and we can set up a call to discuss your goals and objectives for this project. We look forward to hearing from you. Lisa

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