CleanAmp™ dNTPs improve PCR specificity, make PCR reactions cleaner, eliminate or reduce off-target amplicon formation, and are compatible with both Hot Start and non-Hot Start DNA polymerases that employ different buffer compositions (pH 7.5-9, 25°C). CleanAmp™ dNTPs are water soluble, stable for at least 1 year when frozen at –20°C and are inexpensive compared to other Hot Start technologies.